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Double Marker Test in Pregnancy: Cost, Risks and Importance for Baby’s Health

Dr. Pujil Gulati, IVF Specialist with over 13 years of experience in Assisted Reproductive Techniques BabyBloom IVF Gurgaon

June 10, 2025

🧷 What Is the Double Marker Test?

The Double Marker Test is a blood test done in early pregnancy.
It helps doctors know if your baby has a chance of genetic problems, like:

Down syndrome (Trisomy 21)
Trisomy 18 (Edwards syndrome)

This test does not harm the baby. It only gives a risk score to help parents make the right decision.

🕐 When Is It Done?

🩺 This test is usually done between Week 10 and Week 14 of pregnancy.
It is part of the first-trimester screening process.

🧪 What Does It Check?

The blood test checks the levels of two substances in the mother’s blood:

Test Marker	What It Means
hCG	A hormone made during pregnancy
PAPP-A	A protein linked to baby’s growth

These levels are combined with ultrasound data (NT scan) and mother’s age to find out any risk of genetic problems.

👩‍⚕️ Why Is It Important?

This test is important because it:

Helps check for early birth defects
Tells if the baby is at low or high risk of problems
Helps doctors guide you better
Gives mental peace if results are normal

👉 It’s non-invasive, meaning there is no risk to the baby.

💰 What Is the Cost of Double Marker Test?

The cost depends on the city, hospital, and lab. On average:

Location	Approximate Cost (INR)
Metro cities	₹2,000 – ₹3,500
Small towns	₹1,200 – ₹2,500

✅ Some health insurance policies may cover it — ask your provider.

⚠️ Are There Any Risks?

No, there are no physical risks to the mother or baby.
But remember:

This is not a final result, it is only a screening
If your report shows high risk, don’t panic
You may be asked to take more tests like NIPT or Amniocentesis

🧬 What If the Report Is Positive?

Positive or high risk doesn’t mean your baby is unhealthy.
It just means:

You need more tests
Your doctor will explain everything
You and your family can decide the next steps

👉 A genetic counselor may also talk to you and guide your decision.

✅ How to Prepare for This Test?

You don’t need to do anything special.

No fasting required
Just go for your blood test and NT scan
Relax and stay calm – it’s just a routine check

📝 Summary Table – Quick View

Question	Answer
What is it?	Blood test to check baby’s risk of genetic issues
When is it done?	Between 10–14 weeks of pregnancy
What does it check?	hCG and PAPP-A in mother’s blood
Is it safe?	Yes, 100% safe for mom and baby
What is the cost?	₹1,200 – ₹3,500 depending on city
What happens if result is high?	More tests like NIPT may be needed

❓FAQs – Doubts Every Mom Has

Q. Is this test compulsory?

👉 No, but it is highly recommended to detect risks early.

Q. Can I skip the Double Marker Test?

👉 Yes, but then you might miss signs of early problems.

Q. What happens if I miss the time window?

👉 Your doctor may suggest other second-trimester tests like triple marker or quad marker.

Q. Will a positive report mean the baby is unhealthy?

👉 Not always. It only shows chance, not a confirmed problem.

🔚 Conclusion

The Double Marker Test is a safe and helpful way to know about your baby’s health early.
It gives you a head start to manage things if something is not right.

🎯 Remember, a high-risk result is not a final answer – it’s just a signal to check more.

👉 Talk to your doctor. Be informed. Be calm. You’re doing great!

OR If you need any information related to IVF, contact our Babybloom IVF Centre or call us at 9266046700 to clear your doubt.